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_1 |
General Information About Adult Acute Lymphoblastic Leukemia (ALL) |
adult acute lymphoblastic leukemia
Prognosis--legacy
General Information About Adult Acute Lymphoblastic Leukemia (ALL)
ALL (also called acute lymphocytic leukemia) is an aggres |
Changes to This Summary (02/13/2013) |
General Information About Adult Acute Lymphoblastic Leukemia |
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Stage Information for Adult ALL |
adult acute lymphoblastic leukemia
Stage explanation--legacy
Stage Information for Adult ALL
There is no clear- |
Treatment Option Overview |
Disease Status |
X |
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Remission induction therapy |
Remission induction therapy
Sixty percent to 80% of adults with ALL usually achieve a complete remission (CR) status following appropria |
Treatment Option Overview |
Remission induction therapy |
X |
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Standard Treatment Options for Untreated Adult ALL |
Remission induction therapy |
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X |
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CNS prophylaxis therapy |
CNS prophylaxis therapy
The early institution of CNS prophylaxis is critical to achieve control of
sanctuary disease.
Consider adding text |
Treatment Option Overview |
CNS prophylaxis therapy |
X |
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Standard Treatment Options for Untreated Adult ALL |
Central nervous system (CNS) prophylaxis therapy |
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X |
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Postremission therapy |
Postremission therapy
Current approaches to postremission therapy for adult ALL include short-term, relatively intensive chemotherapy followed by |
Treatment Option Overview |
Postremission therapy |
X |
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Standard Treatment Options for Adult ALL in Remission |
Postremission therapy |
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X |
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CNS prophylaxis therapy |
CNS prophylaxis therapy
The early institution of CNS prophylaxis is critical to achieve control of
sanctuary disease. Some authors have suggested |
Treatment Option Overview |
CNS prophylaxis therapy |
X |
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Standard Treatment Options for Adult ALL in Remission |
Central nervous system (CNS) prophylaxis therapy |
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X |
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Reinduction chemotherapy |
Reinduction chemotherapy
Patients with ALL who experience a relapse following chemotherapy and maintenance
therapy are unlikely to be cured by fur |
Treatment Option Overview |
Reinduction chemotherapy |
X |
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Standard Treatment Options for Recurrent Adult ALL |
Reinduction chemotherapy |
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X |
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Palliative radiation therapy |
Palliative radiation therapy
Low-dose palliative radiation
therapy may be considered in patients with symptomatic recurrence either within
or outs |
Treatment Option Overview |
Palliative radiation therapy |
X |
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Standard Treatment Options for Recurrent Adult ALL |
Palliative radiation therapy |
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X |
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Dasatinib |
Dasatinib
Patients with Ph1-positive ALL will often be taking imatinib at the time of relapse and thus will have imatinib-resistant disease. Dasa |
Treatment Option Overview |
Dasatinib |
X |
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Standard Treatment Options for Recurrent Adult ALL |
Dasatinib |
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X |
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Cellular Classification of Adult ALL |
Table Frequency of ALL Cell SubtypesCell SubtypeApproximate FrequencyEarly B-cell lineage80% T cells10%–15%B cells with surface immunoglobulins<5% |
Cellular Classification of Adult ALL |
None |
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Incidence and Mortality |
Estimated new cases and deaths from ALL in the United States in 2013:Cancer Facts and Figures 2013 |
Changes to This Summary (02/13/2013) |
statistics |
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